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San Francisco 49ers schedule: Difficult slate awaits defending NFC West champs

The San Francisco 49ers schedule for 2023 has not yet been released. However, we do know who their opponents will be for next season. Below is a look at the 49ers’ 2023 opponents with a quick check at their updated depth chart.

2023 San Francisco 49ers schedule (opponents)

  • Home: Arizona Cardinals, Los Angeles Rams, Seattle Seahawks, Dallas Cowboys, New York Giants, Baltimore Ravens, Cincinnati Bengals, Tampa Bay Buccaneers
  • Away: Arizona Cardinals, Los Angeles Rams, Seattle Seahawks, Washington Commanders, Pittsburgh Steelers, Cleveland Browns, Philadelphia Eagles, Jacksonville Jaguars, Minnesota Vikings

San Francisco 49ers schedule highlights: San Francisco’s schedule for the 2023 includes 10 games against teams that earned a playoff spot a season ago.

San Francisco 49ers depth chart outlook

  • QB — Brock Purdy, Trey Lance, Sam Darnold
  • RB — Christian McCaffrey, Elijah Mitchell, Tyrion Davis-Price, Jordan Mason
  • FB — Kyle Juszczyk
  • TE — George Kittle, Cameron Latu (R), Ross Dwelley, Brayden Willis (R)
  • WR — Deebo Samuel, Brandon Aiyuk, Jauan Jennings, Danny Gray, Ray-Ray McCloud, Chris Conley, Willie Snead, Ronnie Bell (R)
  • NFL offense rankings: 7th
  • NFL defense rankings: 1st
  • NFL power rankings: 3rd

San Francisco 49ers schedule: Season results

NFL: San Francisco 49ers at Los Angeles Rams
Gary A. Vasquez-USA TODAY Sports

Week 1 — San Francisco 49ers lose to Chicago Bears, 19-10

DateOpponentTime (ET)TV
Sunday, Sep 11Bears 19, 49ers 101:00 PM FOX
  • 49ers @ Bears point spread: San Francisco -6.5
  • Sportsnaut prediction: 49ers 27, Bears 17

Week 2 — 49ers crush Seattle Seahawks 27-7

DateGameTime (ET)TV Info
Sunday, Sep. 1849ers 27, Seahawks 74:05 PM FOX
  • Seahawks @ 49ers point spread: 49ers -8.5
  • Prediction: 49ers 28, Seahawks 17

Week 3: 49ers stumble in boring loss to Broncos, 11-10

DateGameTime (ET)TV Info
Sunday, Sep. 25Broncos 11, 49ers 108:20 PM NBC
  • 49ers @ Broncos point spread: 49ers +2.5
  • Sportsnaut’s prediction: Broncos 31, 49ers 23

Week 4 — San Francisco 49ers defeat the Los Angeles Rams, 24-9

DateGameTime (ET)TV Info
Monday, Oct. 349ers 24, Rams 98:15 PM ESPN

Week 5 — San Francisco 49ers blast Carolina Panthers, 37-15

DateGameTime (ET)TV Info
Sunday, Oct. 949ers 37, Panthers 154:05 PM CbS
  • Point spread: 49ers -6.5
  • Prediction: 49ers 27, Panthers 10

Week 6 — San Francisco 49ers lose to the Atlanta Falcons, 28-14

DateGameTime (ET)TV Info
Sunday, Oct. 16Falcons 28, 49ers 141:00 PM FOX
  • Point spread: -6.5
  • Prediction: 49ers 35, Falcons 17

Week 7 — San Francisco 49ers smashed by Chiefs, 44-23

DateGameTime (ET)TV Info
Sunday, Oct. 23Chiefs 44, 49ers 234:25 PM FOX
  • Point spread: Chiefs -1.5
  • Prediction: Chiefs 31, 49ers 21

Week 8 — San Francisco 49ers pound Rams, 31-14

DateGameTime (ET)TV Info
Sunday, Oct. 3049ers 31, Rams 144:25 PM FOX

Week 10 — San Francisco 49ers slow down Chargers for 22-16 win

DateGameTime (ET)TV Info
Sunday, Nov. 1349ers 22, Chargers 168:20 PM NBC
  • Chargers @ 49ers point spread: San Francisco -3.5
  • Prediction: 49ers 27, Chargers 24

Week 11: San Francisco 49ers destroy Arizona Cardinals in 38-10 win

DateGameTime (ET)TV Info
Monday, Nov. 2149ers 38, Cardinals 108:15 PM ESPN
Located at Estadio Azteca, in Mexico City
  • 49ers @ Cardinals point spread: San Francisco -8.5
  • Prediction: 49ers 27, Cardinals 17

Week 12 — San Francisco 49ers shutout New Orleans Saints, 13-0

DateGameTime (ET)TV Info
Sunday, Nov. 2749ers 13, Saints 04:25 PM FOX
  • 49ers vs Saints point spread: 49ers -8.5
  • Prediction: 49ers 27, Saints 16

Week 13 — San Francisco 49ers beat the Miami Dolphins, 33-17

DateGameTime (ET)TV Info
Sunday, Dec. 449ers 33, Dolphins 174:05 PM FOX
  • Point spread: 49ers -4.5
  • Prediction: 49ers 24, Dolphins 20

Week 14 — San Francisco 49ers beat Tampa Bay Buccaneers, 35-7

DateGameTime (ET)TV Info
Sunday, Dec. 1149ers 35, Buccaneers 74:25 PM FOX
  • Prediction: 49ers 27, Buccaneers 14

Week 15 — San Francisco 49ers beat Seattle Seahawks, 21-13

DateGameTime (ET)TV Info
Thursday, Dec. 1549ers 21, Seahawks 138:15 PM Prime Video
  • Prediction: 49ers 30, Seahawks 14

Week 16: San Francisco 49ers beat Washington Commanders, 37-20

DateGameTime (ET)TV Info
Saturday, Dec. 2449ers 37, Commanders 204:05 PM CBS
  • Prediction: 49ers 31, Commanders 16

Week 17: San Francisco 49ers lead thrilling win over Las Vegas Raiders

DateGameTime (ET)TV INFO
Sunday, Jan. 149ers 37, Raiders 34 (OT)4:05 PM FOX
  • Prediction: 49ers 27, Raiders 24

Week 18: San Francisco 49ers pummel Cardinals 38-13

DateGameTime (ET)TV Info
Sun, Jan. 849ers 38, Cardinals 134:25 PMFOX
  • Prediction: 49ers 27, Cardinals 20

Wild Card: San Francisco 49ers continue dominance with win over Seahawks

DateGameTime (ET)TV Info
Sat. Jan. 1449ers 41, Seahawks 234:30 PMFOX
  • Prediction: 49ers 24, Seahawks 17

Divisional Round: San Francisco 49ers eliminate Dallas Cowboys again

DateGameTime (ET)TV Info
Sun. Jan. 2249ers 19, Cowboys 126 PMFOX
  • Prediction: 49ers 24, Cowboys 17

NFC Championship: San Francisco 49ers’ injury issues end exciting season

DateGameTime (ET)TV Info
Sun. Jan. 29Eagles 31, 49ers 73 PMFOX
  • Prediction: 49ers 24, Eagles 21

2022-2023 San Francisco 49ers record: 13-4

San Francisco 49ers schedule, predictions
Credit: Kyle Terada-USA TODAY Sports
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