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San Francisco 49ers injury report: Richard Sherman nears return, COVID-19 outbreak

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San Francisco 49ers injury report: The San Francisco 49ers head into their Week 12 outing against the Los Angeles Rams losers of three consecutive and on the verge of falling completely out of the NFC Playoff picture.

San Francisco has been ravaged by injuries this season, losing multiple starters on both sides of the ball. Beyond season-ending injuries to the likes of George Kittle, Nick Bosa and Solomon Thomas, the 49ers will also be without key players in Week 12. They are also dealing with a major COVID-19 outbreak, something that impacted the team earlier in the season.

Here’s your latest San Francisco 49ers injury report heading into Week 12.

Updated: Nov. 23, 5:19 PM EST

San Francisco 49ers schedule

  • Week 12: San Francisco at Los Angeles
  • Week 13: Buffalo at San Francisco
  • Week 14: Washington at San Francisco
  • Week 15: San Francisco at Dallas
  • Week 16: San Francisco at Arizona
  • Week 17: Seattle at San Francisco

San Francisco 49ers injury report: COVID-19 list

Arik Armstead, defensive line
Javon Kinlaw, defensive line
Hroniss Grasu, center
Joe Walker, linebacker
Brandon Aiyuk, wide receiver
Daniel Helm, tight end
Trent Williams, offensive tackle
D.J. Jones, defensive line
Jordan Willis, defensive line

Now there’s a good chance that most of these players will be cleared ahead of Sunday’s game against the Rams. If, for some reason, that’s not the case, San Francisco is looking at missing six more starters in addition to the plethora of injuries it has dealt with.

Related: 2022 NFL Power Rankings – Outlook for all 32 teams entering summer

Jimmy Garoppolo injury update

  • Position: QB
  • Status: Out
  • Injury: Ankle
  • Team impact: Garoppolo is out a minimum of six weeks after aggravating his high-ankle sprain. According to ESPN’s Adam Schefter, the quarterback is out for a minimum of six weeks. If surgery is required, he’ll miss the remainder of the season. For now, this means Nick Mullens will be under center for the 49ers. He came in and threw for 238 yards and two touchdowns in the fourth quarter alone against Seattle in Week 8. Mullens then followed that up by throwing two touchdowns compared to three interceptions in two starts, both losses.
  • Fantasy impact: Not much to look at here. Garoppolo was a mid-tier QB2 heading into the season. Nothing really changed on that front prior to him suffering this injury back in Week 2. Mullens could be a play in daily fantasy leagues dependent on the matchup. Specific to Week 12, we’re avoiding him against an elite Rams defense.

George Kittle injury update

  • Position: TE
  • Status: Out
  • Injury: Foot
  • Team impact: Kittle is more than likely out for the season after suffering a broken bone in his foot during Week 8’s loss to the Seahawks. Obviously, it’s some pretty bad news for this injury-plagued squad. Kittle had recorded 37 receptions for 474 yards in six games prior to suffering said injury. San Francisco will likely play it in a cautionary manner with the NFL’s best tight end, especially if the team finds itself out of the playoff race here soon.
  • Fantasy impact: Two words. Jordan Reed. This former Pro Bowler put up five receptions for 62 yards against the Saints in Week 10. It was his second game back after missing five outings. Prior to that, Reed looked great earlier in the season. That included a two-touchdown performance against the Jets in Week 2. With Mullens under center, he becomes a viable TE1 option. Remember, Kittle caught all 15 of his targets from Mullens back in Week 4.

Related: NFL Week 12 injury report

Tevin Coleman injury update

  • Position: RB
  • Status: Questionable
  • Injury: Knee
  • Team impact: Coleman had missed the past five games prior to Week 8. He was activated off injured reserve, only to leave in the first quarter after putting up 20 yards on three attempts. He’s now missed two consecutive games and is questionable to go Week 12.
  • Fantasy impact: Coleman was in no way a relevant fantasy option. That’s until rookie undrafted free agent JaMycal Hasty suffered a high-ankle sprain back in Week 10. San Francisco is now incredibly thin at running back. Raheem Mostert is questionable to go after missing the past few weeks. Jeff Wilson remains on injured reserve. Even then, Jerick McKinnon would seem to be a better bet in daily leagues.

Deebo Samuel injury update

49ers' Jimmy Garoppolo and Deebeo Samuel against Rams, NFL Week 6
October 18, 2020; Santa Clara, California, USA; San Francisco 49ers wide receiver Deebo Samuel (19) is congratulated by quarterback Jimmy Garoppolo (10) for scoring a touchdown against the Los Angeles Rams during the first quarter at Levi’s Stadium. Mandatory Credit: Kyle Terada-USA TODAY Sports
  • Position: Wide receiver
  • Status: Questionable
  • Injury: Hamstring
  • Team impact: Huge. Absolutely huge. 49ers head coach Kyle Shanahan noted ahead of the 49ers’ Week 11 bye that they are hopeful to get Samuel back for Week 12 against the Rams. It goes without saying he’s a dynamic receiving and running threat in this offense.
  • Fantasy impact: Equally as important for the fantasy football world, Samuel has proven to be a FLEX option in daily leagues. He put up 11 receptions for 131 yards and one touchdown on 11 targets in two games prior to suffering this injury. If Samuel does return Week 12, he becomes an immediate FLEX option. If not, Brandon Aiyuk (should he play) remains viable. The rookie has put up 21 receptions for 281 yards over the past three games.

Jeff Wilson injury update

  • Position: Running back
  • Status: Out (IR)
  • Injury: High-ankle sprain
  • Team impact: Wilson entered the season as San Francisco’s No. 4 running back. Obviously, the multitude of injuries at this position has impacted his ability to contribute. The former undrafted free agent from North Texas put up 120 total yards and three touchdowns against New England before suffering this injury. Over the course of the past two seasons, Wilson has scored 10 touchdowns on just 74 touches. That’s crazy.
  • Fantasy impact: With Wilson out and Coleman and Mostert questionable, Jerick McKinnon will probably see a nice amount of reps against Green Bay. He was pretty much held out of Week 7’s win over the Patriots because Kyle Shanahan wanted to give the injury-plagued back some reps. Depending on the 49ers’ final injury report, McKinnon becomes a solid option (as we mentioned above).

Related: NFL Week 12 schedule, predictions

Raheem Mostert injury update

  • Position: Running back
  • Status: Questionable
  • Injury: High-ankle sprain
  • Team impact: In just his second game after returning from a sprained ACL, Mostert injured his ankle against the Rams back in Week 6. It came after he put up 195 total yards in just six quarters. When healthy and on the field, Mostert is among the most-electric backs in the NFL. He’s averaging a ridiculous 7.3 yards per touch on the season. Unfortunately, the 49ers’ offense is much different when Mostert is not on the field.
  • Fantasy impact: The hope is that Mostert will be able to go Week 12 and is not limited. It could make for a big game given San Francisco will be relying on its rushing attack against a great Rams pass defense. The one area the Rams have struggled on that side of the ball to an extent this season is stopping the run.

Nick Bosa injury update

  • Position: Defensive end
  • Status: Out (injured reserve)
  • Injury: Torn ACL
  • Team Impact: Obviously, this is a major blow for the 49ers. Missing out on their top defensive player for the remainder of the season is going to hurt big time. Bosa, 22, recorded 25 quarterback hits and nine sacks last season.
  • Fantasy Impact: The 49ers are also without Dee Ford (injured reserve) for Sunday’s game against the Seahawks. This shouldn’t impact the fantasy world too much. Russell Wilson was going to be a top-end QB1 option in the first place.

Richard Sherman injury update

  • Position: Starting cornerback
  • Status: Questionable
  • Injury: Calf
  • Team impact: The hope is that Sherman will be back on the field Sunday after being out since all the way back in Week 2. A lot of that will depend on how practice goes this week. Needless to say, San Francisco needs their future Hall of Fame corner back on the field.
  • Fantasy impact: With how good Jason Verrett has played this season, getting Sherman back against the Rams could have wide-ranging fantasy ramifications. Primarily, Robert Woods and Josh Reynolds become less-relevant fantasy options.

Related: If you’re a fan of the 49ers, check out #NinerNation rumors, rankings, and news here.

Dee Ford injury update

  • Position: Defensive end
  • Status: Out
  • Injury: Back, neck (injured reserve)
  • Team Impact: A blockbuster acquisition of the 49ers ahead of the 2019 season, Ford suffered through an injury-plagued first campaign with the team. He recorded 6.5 sacks in 11 games. With that said, San Francisco’s defense was a complete monster with both Ford and Bosa on the field.
  • Fantasy Impact: As noted before, being without both Bosa and Ford is going to loom large. San Francisco will now need to rely on Arik Armstead and rookie first-round pick Javon Kinlaw. This could be something to watch moving forward. For now, the 49ers are struggling getting to the quarterback.
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