The San Francisco 49ers head into their Week 7 outing against the New England Patriots coming off an impressive win over the Los Angeles Rams last Sunday. The backdrop here has been injury after injury San Francisco has had to deal with throughout the season. San Francisco needs to pick up with that momentum as the injury-plagued teams looks to remain viable in the NFC West.

Jimmy Garoppolo finally looked like himself in Week 6 after struggling with the ankle injury during the previous game. Raheem Mostert suffered another injury that has now landed him on injured reserve.

Below, we break down the 49ers’ injuries as the 3-3 team heads into another must-win game against the Patriots Week 7.

Updated: Oct. 23, 1:40 AM EST

Related: NFL Week 7 power rankings

San Francisco 49ers schedule

  • Week 7: San Francisco at New England
  • Week 8: San Francisco at Seattle
  • Week 9: Green Bay at San Francisco
  • Week 10: San Francisco at New Orleans

Raheem Mostert injury update

49ers running back Raheem Mostert
Jan 19, 2020; Santa Clara, California, USA; San Francisco 49ers running back Raheem Mostert (31) celebrates the victory against the Green Bay Packers following the NFC Championship Game at Levi’s Stadium. Mandatory Credit: Cary Edmondson-USA TODAY Sports
  • Position: Running back
  • Status: Out (injured reserve)
  • Injury: High-ankle sprain
  • Team impact: In just his second game after returning from a sprained ACL, Mostert injured his ankle against the Rams this past Sunday. It came after he put up 195 total yards in just six quarters. When healthy and on the field, Mostert is among the most-electric backs in the NFL. He’s averaging a ridiculous 7.3 yards per touch on the season. Unfortunately, the 49ers’ offense is much different when Mostert is not on the field. Now that he’s out at least three weeks, this is a major concern.
  • Fantasy impact: Jerick McKinnon and undrafted rookie Jamycal Hasty will likely split carries on Sunday with fellow running back Jeff Wilson also questionable to go. For his part, McKinnon is on pace for nearly 900 total yards and is averaging an awesome 5.7 yards per touch this season. He’s a decent FLEX option in daily contests like DraftKings.

Jimmy Garoppolo injury update

  • Position: Quarterback
  • Status: Will play
  • Injury: High-ankle sprain
  • Team Impact: Garoppolo practiced in full this week and is now officially off the 49ers’ injury report. That’s great news for San Francisco heading into Week 7. When he’s 100% healthy, Garoppolo can be a top-10 quarterback in the NFL.
  • Fantasy Impact: Garoppolo does not have a great matchup against his former Patriots team. Their defense has yielded nine passing touchdowns compared to six interceptions in five games. While Garoppolo is not a relevant fantasy option, tight end George Kittle should still continue to eat. Kittle has caught 30-of-38 targets in four games this season.

Related: NFL Week 7 schedule, predictions

Nick Bosa injury update

  • Position: Defensive end
  • Status: Out (injured reserve)
  • Injury: Torn ACL
  • Team Impact: Obviously, this is a major blow for the 49ers. Missing out on their top defensive player for the remainder of the season is going to hurt big time. Bosa, 22, recorded 25 quarterback hits and nine sacks last season.
  • Fantasy Impact: The 49ers are also without Dee Ford (injured reserve) for Sunday’s game against the Patriots. This shouldn’t impact the fantasy world too much. Cam Newton was going to be a bottom-end QB1 option in the first place.

Related: How rash of injuries impacts NFL trade deadline

Jordan Reed injury update

Position: Tight End

Status: Out

Injury: Knee (injured reserve)

Team Impact: Reed’s injury coincided with the return of George Kittle from a two-game absence. In reality, the 49ers will take this trade off every day of the week. Kittle responded by catching all 15 of his targets for 183 yards against Philadelphia Eagles in Week 5. All said, Kittle has hauled in 30-of-38 targets this season.

Fantasy Impact: Reed is expected to be out the next 2-4 weeks. If you decided to roster him after that two-touchdown performance against the Jets, move on. As for Kittle, he’s taking on a Patriots defense that’s allowing an average of just three receptions per game to tight ends. As always, Kittle is a TE1 in fantasy leagues.

Related: NFL Week 7 injury report

Tevin Coleman injury update

  • Position: Running back
  • Status: Out
  • Injury: Knee
  • Team Impact: Coleman has touched the ball 21 times in two games, averaging a poor 3.0 yards per touch. That’s not going to get it done in Kyle Shanahan’s running back-friendly offense. This injury moves other more promising backs up a notch on the depth chart.
  • Fantasy Impact: Pretty much nothing. Mostert will continue to see a bulk of the carries for San Francisco once he returns with McKinnon being sprinkled in. For now, McKinnon is the only fantasy-relevant option in the 49ers’ backfield.

Richard Sherman injury update

  • Position: Starting cornerback
  • Status: Out (injured reserve)
  • Injury: Calf
  • Team impact: San Francisco’s decision not to add another starter-caliber corner during the offseason is now magnified. Emmanuel Moseley and Ahkello Witherspoon are not the answers. Relying on a player in Jason Verrett who has suited up in five games since the end of the 2015 season is also problematic. However, he’s looked great.
  • Fantasy impact: Sherman was eligible to come off injured reserve last week. However, the 49ers have held him out of practice and decided not to play him in Week 6. At this point, it seems like Sherman will be out until Week 12. With that said, not a single Patriots receiver is a fantasy-relevant option in Week 7.

Related: NFL Week 7 fantasy rankings

Dee Ford injury update

  • Position: Defensive end
  • Status: Out
  • Injury: Back, neck (injured reserve)
  • Team Impact: A blockbuster acquisition of the 49ers ahead of the 2019 season, Ford suffered through an injury-plagued first campaign with the team. He recorded 6.5 sacks in 11 games. With that said, San Francisco’s defense was a complete monster with both Ford and Bosa on the field.
  • Fantasy Impact: As noted before, being without both Bosa and Ford is going to loom large. San Francisco will now need to rely on Arik Armstead and rookie first-round pick Javon Kinlaw. This could be something to watch moving forward. For now, the 49ers are struggling getting to the quarterback.
Vincent Frank
Editor here at Sportsnaut. Contributor at Forbes. Previous bylines include Bleacher Report, Yahoo!, SB Nation. Heard on ESPN Radio and NBC Sports Radio. Northern California native living it up in Las Vegas. The Keto lifestyle. Traveler. Reader. TV watcher. Dog daddy. Sam Malone = greatest TV character ever. "Carpe diem. Seize the day, boys. Make your lives extraordinary," John Keating.