Buffalo Bills schedule
| Game | Date | Time (ET) | TV |
| Bills @ Chiefs | Sunday, January 23 | 6:30 PM | CBS, Paramount + |
- Point spread: Chiefs -1.5
- Over/under: 54.5
- Moneyline: Bills +110; Chiefs -130
- Sportsnaut prediction: Bills 31, Chiefs 28
Buffalo Bills roster outlook
- QB — Josh Allen, Mitchell Trubisky
- RB — Devin Singletary, Zack Moss, Matt Breida
- TE — Dawson Knox, Tommy Sweeney
- WR — Stefon Diggs, Cole Beasley, Gabriel Davis, Emmanuel Sanders
- Defense — Bills rank 4th in defense this week
Buffalo Bills’ season results (11-6 record)
Week 1 — Buffalo Bills lost at home to the Pittsburgh Steelers, 23-16
- When: Sunday, Sept. 12 at 1:00 PM on CBS
- Spread: Bills -6.5
- Moneyline: Steelers +240; Bills -300
- Sportsnaut prediction: Bills 24, Steelers 17
Week 2 — Buffalo Bills beat Miami Dolphins on the road, 35-0
- When: Sunday, September 19 at 1:00 PM EST
- Spread: Bills -3
- Moneyline: Dolphins +145; Bills -175
- Over/under: 47.5
- Sportsnaut prediction: Dolphins 27, Bills 24
Week 3 — Buffalo Bills beat Washington Football Team at home, 43-21
- When: Sunday, September 26 at 1:00 PM EST
- Spread: Bills -7.0 (BetMGM)
- Moneyline: Bills (-450), WF (+350)
- Over/under: 45.5
- Sportsnaut prediction: Bills 20, Washington 14
Week 4 — Buffalo Bills beat Houston Texans, 40-0
- When: Sunday, October 3 at 1:00 PM EST
- Point spread: Bills -16.5
- Moneyline: Texans +750; Bills -1300
- Over/under: 47.0
- Sportsnaut prediction: Bills 45, Texans 10
Week 5 — Buffalo Bills beat Kansas City Chiefs, 38-20
- When: Sunday, October 10 at 8:20 PM EST on NBC
- Point spread: Chiefs -2.5
- Moneyline: Bills +120; Chiefs -145
- Over/under: 56.5
- Sportsnaut prediction: Bills 35, Chiefs 31
Week 6 — Buffalo Bills lose to the Tennessee Titans, 34-31
- When: Monday, October 18 at 8:15 PM EST on ESPN
- Point spread: Bills -6.0
- Moneyline: Titans +210; Bills -260
- Over/under: 53.5
- Sportsnaut prediction: Bills 34, Titans 23
Week 8 — Buffalo Bills beat the Miami Dolphins, 26-11
- When: Sunday, October 31 at 1:00 PM
- Point spread: Bills -14.0
- Moneyline: Dolphins +575; Bills -800
- Over/under: 48.0
- Sportsnaut prediction: Bills 38, Dolphins 17
Week 9 — Buffalo Bills lose to Jacksonville Jaguars, 9-6
- When: Sunday, November 7 at 1:00 PM EST
- Point spread: Bills -14.5
- Moneyline: Jaguars +625; Bills -1000
- Over/under: 48.5
- Sportsnat prediction: Bills 42, Jaguars 13
Week 10 — Buffalo Bills beat New York Jets, 45-17
- When: Sunday, November 14 at 1:00 PM EST
- Point spread: Bills -12.0
- Moneyline: Jets +500; Bills -700
- Over/under: 47.5
- Sportsnaut prediction: Bills 41, Jets 13
Week 11 — Buffalo Bills lose to Indianapolis Colts, 41-15
- When: Sunday, November 21 at 1:00 PM EST
- Point spread: Bills -7.0
- Moneyline: Colts +240; Bills -300
- Over/under: 50.0
- Sportsnaut prediction: Bills 31, Colts 23
Week 12 — Buffalo Bills beat the New Orleans Saints (TNF), 31-6
- When: Thursday, Nov. 25 at 8:20 PM EST
- Point spread: Bills -5.5
- Moneyline: Saints +200; Bills -240
- Over/under: 45.5
- Sportsnaut prediction: Bills 31, Saints 20
Week 13 — Buffalo Bills lost to the New England Patriots, 14-10
- When: Monday, Dec. 6 at 8:15 PM EST on ESPN
- Point spread: Bills -2.5
- Moneyline: Patriots +125; Bills -150
- Over/under: 42.5
- Sportsnaut prediction: Patriots 24, Bills 21
Week 14 — Buffalo Bills lose to Tampa Bay Buccaneers, 33-27 in OT
- When: Sunday, Dec. 12 at 4:25 PM EST
- Point spread: Buccaneers 3.5
- Moneyline: Bills +155; Buccaneers -185
- Over/under: 52.5
- Sportsnaut prediction: Buccaneers 31, Bills 28
Week 15: Buffalo Bills beat Carolina Panthers, 31-14
- When: Sunday, December 19 at 1:00 PM EST
- Point spread: Bills -10.5
- Over/under: 44.5
- Moneyline: Panthers +375; Bills -500
- Sportsnaut prediction: Bills 38, Panthers 17
Related: Updated NFL defense rankings
Week 16 — Buffalo Bills beat New England Patriots, 33-21
- When: Sunday, December 26 at 1:00 PM ET
- Point spread: Patriots -2.0
- Over/under: 43.0
- Moneyline: Bills +115; Patriots -135
- Sportsnaut prediction: Bills 27, Patriots 23
Week 17 — Buffalo Bills beat Atlanta Falcons, 29-15
- When: Sunday, January 2 at 1:00 PM ET
- Point spread: Bills -14.5
- Over/under: 44.5
- Moneyline: Falcons +600; Bills -900
- Sportsnaut prediction: Bills 40, Falcons 17
Week 18 — Buffalo Bills beat New York Jets, 27-10
- When: Sunday, January 9 at 1:00 PM
- Point spread: Bills -16.5
- Over/under: 41.0
- Moneyline: Jets +1000; Bills -2000
- Sportsnaut prediction: Bills 35, Jets 13
AFC Wild Card Playoffs — Buffalo Bills beat New England Patriots, 47-17
- When: Saturday, January 15 at 8:15 PM ET
- Point spread: Chiefs -1.5
- Over/under: 44.0
- Moneyline: Patriots +175; Bills -200
- Sportsnaut prediction: Bills 27, Patriots 23