Who will win the World Series? The 2025 MLB season is underway with the Los Angeles Dodgers seeking to defend their World Series titles. Injuries have already been a central part of spring training with the New York Yankees and New York Mets hit the hardest by injuries. With the arrival of Opening Day, we’re looking at World Series odds 2025 to help determine potential picks for the 2025 season.
It will come as no surprise that the Dodgers are the heavy favorites to win the World Series. If it happens, Los Angeles would be the first team since the 1998-2000 Yankees to win the title in consecutive seasons. With the regular season just starting, we’re highlighting favorites and sleepers to win the World Series this year.
Read: Highest paid MLB players 2025
World Series odds 2025: Opening Day odds for all 30 teams
| Team | ESPN | FanDuel |
|---|---|---|
| Los Angeles Dodgers | +275 | +240 |
| Atlanta Braves | +800 | +850 |
| New York Yankees | +850 | +900 |
| New York Mets | 10-1 | +1100 |
| Philadelphia Phillies | 10-1 | +1000 |
| Baltimore Orioles | 12-1 | +1600 |
| Houston Astros | 14-1 | +1800 |
| San Diego Padres | 16-1 | +3300 |
| Boston Red Sox | 20-1 | +1800 |
| Texas Rangers | 25-1 | +1900 |
| Seattle Mariners | 25-1 | +3000 |
| Cleveland Guardians | 25-1 | +3500 |
| Arizona Diamondbacks | 25-1 | +3300 |
| Minnesota Twins | 30-1 | +3000 |
| Detroit Tigers | 30-1 | +3000 |
| Chicago Cubs | 30-1 | +3000 |
| Kansas City Royals | 40-1 | +4000 |
| Milwaukee Brewers | 50-1 | +5000 |
| Tampa Bay Rays | 50-1 | +5000 |
| San Francisco Giants | 60-1 | +10000 |
| Cincinnati Reds | 60-1 | +7500 |
| Toronto Blue Jays | 60-1 | +6500 |
| St. Louis Cardinals | 60-1 | +14000 |
| Pittsburgh Pirates | 75-1 | +15000 |
| Los Angeles Angels | 150-1 | +18000 |
| Sacramento Athletics | 150-1 | +22000 |
| Washington Nationals | 150-1 | +30000 |
| Miami Marlins | 300-1 | +50000 |
| Colorado Rockies | 400-1 | +50000 |
| Chicago White Sox | 400-1 | +50000 |
Related: MLB Award Predictions 2025
Who will win the World Series? Top picks based on World Series odds
Los Angeles Dodgers – Favorite
The Dodgers have the best roster in MLB. We’ll start with a Dodgers lineup that features three NL MVP candidates – Shohei Ohtani Mookie Betts and Freddie Freeman – sitting atop the bedding order. Behind the trio, Los Angeles boasts All-Star hitters Teoscar Hernandez and Will Smith with Max Muncy rounding out the top half of the lineup. As for the Dodgers rotation, Blake Snell and Yoshinobu Yamamoto are NL Cy Young candidates while Tyler Glasnow and Roki Sasaki could be No. 1 starters for multiple teams. Los Angeles has outstanding pitching depth to support its rotation through injuries and the best bullpen in baseball. It would be a major surprise if the Dodgers aren’t in the World Series this year.
Related: Los Angeles Dodgers game today, Dodgers schedule 2025
New York Yankees – Bust
The New York Yankees roster was decimated by injuries in spring training. It’s a shame because on paper, this team was better than the one that won the American League pennant in 2024. Unfortunately, Gerrit Cole (Tommy John surgery) is lost for the season and All-Star designated hitter Giancarlo Stanton (elbows) could also not play in 2025. New York won’t have reigning AL Rookie of the Year Luis Gil until the summer, which is a best-case scenario for his return. To make matters worse, New York has one of the worst MLB farm systems in 2025 which makes trading for impact players far more challenging. New York simply doesn’t have a playoff-caliber rotation and it didn’t improve enough defensively this winter to overcome the early injuries. Quite frankly, the best bet might be on the Yankees missing the playoffs.
Related: New York Yankees game today, Yankees schedule 2025
Boston Red Sox – Sleeper
The Boston Red Sox might already be the best team in the American League but they enter Opening Day with the ninth-highest World Series odds. Comparing Red Sox to the top AL competition, we would quite easily take Boston’s rotation over the Orioles’ injury-plagued pitching staff. The Red Sox lineup is one of the best in baseball and its bullpen is underrated. Plus, Boston’s farm system would allow the front office to swing an in-season trade for another All-Star to fortify the batting order or the front-line rotation. For whatever reason, the Red Sox are being slept on nationally but they would be our pick to win the AL pennant this season.
Related: Boston Red Sox game today, Red Sox schedule 2025
Arizona Diamondbacks – Darkhorse
Don’t sleep on the Arizona Diamondbacks. This team reached the World Series just two years ago and there’s an argument to be made the Diamondbacks roster is even better now. Thanks to the addition of Corbin Burnes, Arizona boasts a top-five pitching staff which includes bullpen depth for the first time in years. We’re also confident in the Diamondbacks lineup finishing top 10 in runs scored and OPS this season. It will be an uphill climb to overtake the Dodgers, but Arizona stands out as the obvious darkhorse pick based on its World Series odds being aligned with the likes of the Seattle Mariners and Cleveland Guardians.
World Series 2025 prediction: Dodgers over Red Sox in 5 games
We believe the two best MLB teams right now are the Red Sox and Dodgers. The Yankees’ injuries took them out of the running and the American League seems weaker on paper than it’s been in several years. Boston has more depth than before with the premium talent in the rotation (Garrett Crochet) and lineup (Alex Bregman) ti finally turn Boston back into an elite team. However, the Dodgers roster is superior and we believe it will lead to a gentleman’s sweep in the World Series.
- Odds: +2800