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WATCH: 49ers’ Jimmy Garoppolo throws horrible pick-six

Turnovers have been an issue for San Francisco 49ers quarterback Jimmy Garoppolo during the early stages of his career with the team.

That came back to haunt the high-priced quarterback in San Francisco’s season opener against the Tampa Bay Buccaneers on Sunday.

Up 3-0 in the second quarter and facing second and long, Garoppolo was picked off by Bucs cornerback Vernon Hargreaves, who returned it 15 yards for a touchdown.

There’s no excuse for that. What a horrible decision from Garoppolo to throw late to the outside.

That’s a rookie mistake from the fifth-year quarterback. It’s unacceptable.

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