San Francisco 49ers rookie No. 3 pick Trey Lance replaced a hobbled Jimmy Garoppolo under center for Sunday’s game against the Arizona Cardinals.

Getting his first NFL regular-season start, Lance played pretty well. He completed 15-of-29 passes for 192 yards while adding 89 rushing yards on 16 attempts. It wasn’t enough for San Francisco to overcome some big mistakes and bad coaching in a 17-10 loss to Arizona.

With the 49ers now set to hit their bye amid a three-game losing streak, we’re hearing some more bad news on the injury front.

San Francisco head coach Kyle Shanahan told reporters on Monday that Lance suffered a left knee sprain in the loss and could miss some time. The coach noted that it could be a one or two week injury.

With Garoppolo sidelined, this most definitely isn’t the news a struggling 49ers team wanted to hear. If neither quarterback can go Week 7 against the Indianapolis Colts, Nate Sudfeld would likely get the call.

As for what we’ve seen from Trey Lance thus far as a rookie, he’s completing 52.1% of his passes with 354 passing yards and four total touchdowns against one interception.

Either way, the 49ers are expected to go back to Garoppolo once he’s healthy. The injury-plagued quarterback missed Sunday’s game with a calf injury and has been absent for 24 of a possible 53 games since the start of the 2018 campaign.

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An editor here at Sportsnaut. Contributor at Forbes. Previous bylines include Bleacher Report, Yahoo!, SB Nation. Heard on ESPN ... More about Vincent Frank