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The Los Angeles Rams (1-0) face the Indianapolis Colts in Week 2 of the 2021 NFL season. A clash between Matthew Stafford and Carson Wentz should offer plenty of entertainment.
Our Rams vs Colts preview examines the game info, odds and specific matchups that will decide Sunday’s contest.
Find out where the Rams and Colts land in our latest NFL power rankings
Check out our 2021 NFL stadium rankings
Stafford and Sean McVay were smiling all night against the Chicago Bears. The veteran quarterback launched a 67-yard touchdown strike on just his second pass attempt. Finishing the night with 321 passing yards and three touchdowns, the night went about as perfectly as one could hope. As for this upcoming matchup, there will be opportunities to exploit the Colts.
Click here for our Los Angeles Rams game predictions
Wentz made his Colts’ debut in Week 1, throwing two touchdowns and finishing with a 102.0 passer rating. It certainly feels like a great performance, but one of those touchdowns came with the game decided in the closing seconds. He faces a much tougher challenge in Week 2 against the Rams.
Advantage: Matthew Stafford
Indianapolis Colts defensive coordinator Matt Eberflus has been interviewed several times for head-coaching opportunities. Frankly, it wouldn’t be a surprise if he is one of the most coveted candidates in the 2022 coaching cycle. Viewed as one of the best defensive coordinators in the NFL, the Rams vs Colts matchup is a showcase game for him.
Dive into our Indianapolis Colts 2021 season projection
On the others side, McVay is enjoying life. He badly wanted a quarterback who could rip the ceiling off the passing attack that Goff created. We saw that change in effect against the Bears’ woeful secondary. While the Colts have a better reputation, Xavier Rhodes is out Week 2 and that means big plays for the Rams’ receivers.
Advantage: Sean McVay
It took until the final Bears’ offensive drive for Aaron Donald to appear in the box score. But after setting up his teammates for pressures and sacks early, the future Hall of Famer got his moment. He’s impossible to stop across four quarters and Indianapolis is about to learn that real soon.
See where the Rams and Colts land in our NFL defense rankings
This is going to be a challenge for Ryan Kelly. He missed a significant portion of training camp with an elbow injury and appeared rusty against Seattle’s interior defensive line. While the Colts have faced Donald before (2017), this will be Kelly’s first time against him. He’s going to need help and that comes with drawbacks.
Advantage: Aaron Donald
The bottom line: There’s always some difficulty balancing overreactions vs analyzing results from Week 1. But even before the season opener, we were fairly confident Los Angeles was significantly better than Indianapolis. We expect that to play out in this Rams vs Colts game, a potential two-score outcome.