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Arizona Cardinals schedule: Offseason of question marks on the horizon

Vincent Frank
Arizona Cardinals schedule, predictions

Arizona Cardinals schedule: 2022 opponents

  • Home: Los Angeles Rams, San Francisco 49ers, Seattle Seahawks, Kansas City Chiefs, Los Angeles Chargers, Tampa Bay Buccaneers, New Orleans Saints, Philadelphia Eagles, New England Patriots
  • Away: Los Angeles Rams, San Francisco 49ers, Seattle Seahawks, Las Vegas Raiders, Denver Broncos, Atlanta Falcons, Carolina Panthers, Minnesota Vikings

Arizona Cardinals roster outlook

Related: Updated NFL power rankings

Arizona Cardinals’ season results (11-6 record)

Week 1 — Arizona Cardinals defeated the Tennessee Titans on the road, 38-13

  • When: Sunday, Sept. 12 at 1:00 PM on FOX
  • Spread: Titans -3.0
  • Moneyline: Cardinals +125, Titans -152
  • Sportsnaut prediction: Titans 24, Cardinals 20

Week 2 — Arizona Cardinals beat the Minnesota Vikings, 34-33

  • Spread: Cardinals -3.5
  • Moneyline: Vikings +160; Cardinals -190
  • Over/under: 51.0
  • Sportsnaut prediction: Cardinals 28, Vikings 24

Week 3 — Arizona Cardinals win 31-19 @ Jacksonville Jaguars

  • When: Sunday, Sept. 26 at 1:00 PM on FOX
  • Spread: Cardinals -7 (BetMGM)
  • Moneyline: Cardinals (-375), Jaguars (+300)
  • Over/under: 52.0
  • Sportsnaut prediction: Cardinals 34, Jaguars 24

Week 4 — Arizona Cardinals beat Los Angeles Rams, 37-20

  • When: Sunday, October 3 at 4:15 PM EST
  • Point spread: Rams -3.5
  • Moneyline: Cardinals +165; Rams -200
  • Over/under: 54.0
  • Sportsnaut prediction: Rams 28, Cardinals 23

Week 5 — Arizona Cardinals beat San Francisco 49ers, 17-10

  • When: Sunday, October 10 at 4:25 PM EST
  • Point spread: Cardinals -5.0
  • Moneyline: 49ers +190; Cardinals -230
  • Over/under: 50.0
  • Sportsnaut prediction: Cardinals 31-27

Week 6 — Arizona Cardinals beat Cleveland Browns, 37-14

  • When: Sunday, October 17 at 4:25 PM EST
  • Point spread: Browns -3.0
  • Moneyline: Cardinals +145; Browns -175
  • Over/under: 48.0
  • Sportsnaut prediction: Browns 31, Cardinals 24

Week 7 — Arizona Cardinals beat Houston Texans, 31-5

  • When: Sunday, October 24 at 4:05 PM EST
  • Point spread: Cardinals -20.0
  • Moneyline: Texans +1100, Cardinals -2500
  • Over/under: 47.5
  • Week 7 prediction: Cardinals 42, Texans 10

Week 8 — Arizona Cardinals lose to the Green Bay Packers, 24-21

  • Point spread: Cardinals 6.0
  • Moneyline: Packers +210; Cardinals -260
  • Over/under: 51.0
  • Sportsnaut prediction: Cardinals 31, Packers 27

Week 9 — Arizona Cardinals beat San Francisco 49ers, 31-17

  • When: Sunday, November 7 at 4:25 PM EST
  • Point spread: 49ers -5.5
  • Moneyline: Cardinals +210; 49ers -260
  • Over/under: 44.5
  • Sportsnaut prediction: 49ers 28, Cardinals 17

Week 10 — Arizona Cardinals lose to the Carolina Panthers, 34-10

  • When: Sunday, November 14 at 4:05 PM EST
  • Point spread: Cardinals -10.0
  • Moneyline: Panthers +365; Cardinals -500
  • Over/under: 44.5
  • Sportsnaut prediction: Cardinals 35, Panthers 13

Week 11 — Arizona Cardinals beat Seattle Seahawks, 23-13

  • When: Sunday, November 21 at 4:25 PM EST
  • Point spread: Seahawks -3.5
  • Moneyline: Cardinals +145; Seahawks -175
  • Over/under: 45.5
  • Sportsnaut prediction: Seahawks 30, Cardinals 24

Week 13 — Arizona Cardinals beat Chicago Bears, 33-22

  • When: Sunday, December 5 at 1:00 PM EST
  • Point spread: Cardinals -8.0
  • Over/under: 47.0
  • Moneyline: Bears +310; Cardinals -400
  • Sportsnaut prediction: Cardinals 27, Bears 17

Week 14 — Arizona Cardinals lose to Los Angeles Rams, 30-23

  • When: Monday, Dec. 13 at 8:15 PM ET
  • Point spread: Cardinals -2.5
  • Over/under: 51.5
  • Moneyline: Rams +120; Cardinals -145
  • Week 14 prediction: Cardinals 27, Rams 23

Week 15 — Arizona Cardinals lose to Detroit Lions, 30-12

  • When: Sunday, December 19 at 1:00 PM ET
  • Point spread: Cardinals -13.0
  • Over/under: 47.5
  • Moneyline: Lions +550; Cardinals -800
  • Sportsnaut prediction: Cardinals 38, Lions 17

Week 16 — Arizona Cardinals lost to Indianapolis Colts, 22-16

  • Point spread: Cardinals -1.0
  • Over/under: 49.0
  • Moneyline: Colts -105; Cardinals -115
  • Sportsnaut prediction: Colts 23, Cardinals 20

Week 17 — Arizona Cardinals beat Dallas Cowboys, 25-22

  • When: Sunday, January 2 at 4:25 PM ET
  • Point spread: Cowboys -6.0
  • Over/under: 52.0
  • Moneyline: Cardinals +190; Cowboys -230
  • Sportsnaut prediction: Cowboys 27, Cardinals 23

Week 18 — vs. Seattle Seahawks

  • When: Sunday, January 9 at 4:25 PM
  • Point spread: Cardinals -6.5
  • Over/under: 480
  • Moneyline: Seahawks +240; Cardinals -290
  • Sportsnaut prediction: Cardinals 31, Seahawks 20

NFC Wild Card Playoffs — Arizona Cardinals lose to the Los Angeles Rams, 34-11

GameDateTime (ET)TV
Cardinals @ Rams (NFC Wild Card)Monday, January 178:15 PMESPN, ABC, ESPN2
  • When: Monday, January 17 at 8:15 PM ET
  • Point spread: Rams -4.0
  • Over/under: 49.5
  • Moneyline: Cardinals +170; Rams -190
  • Sportsnaut prediction: Rams 31, Cardinals 27