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NFL Week 10 is already upon us. It seems like the season is flying by. As we enter the crunch time ahead of the holiday, preseason odds have given in to reality for some teams. That was obvious for the Dallas Cowboys in Week 9 as their point spread against the Pittsburgh Steelers was something to behold.
Despite this, Dallas held its own with the Steelers. Can we expect the same thing in Week 10 with the Cincinnati Bengals looking to hand Pittsburgh its first lost of the season?
In a game more equally matched, the Indianapolis Colts will take on the Tennessee Titans on Thursday night with first place in the AFC South on the line.
It’s in this that we give you our NFL Week 10 odds and point spreads for each game with a quick piece of information attached.
UPDATED: Nov. 15, 9 AM EST
Related: NFL Week 10 schedule, predictions
NFL Week 10 Sunday games
Houston Texans at Cleveland Browns
Texans-Browns Week 10 odds and point spread: Browns -4.0 (over/under 46.0)
Related: If you’re a fan of the Cleveland Browns, check out #Browns rumors, rankings, and news here
Houston heads into Week 10 2-0 against the Jacksonville Jaguars and 0-6 against the rest of the NFL. In their six losses, the Texans have given up an average of 33.8 points per game. However, the team is also averaging north of four touchdowns per outing since Bill O’Brien was fired. As for the Browns, they are averaging 26 points while giving up 29.6 per outing. Yeah, take the over here.
Washington Football Team at Detroit Lions
Washington-Lions Week 10 odds and point spread: Lions -3.0 (over/under 46.0)
This is an interesting matchup on paper. Washington will now start Alex Smith under center for the remainder of the season after Kyle Allen’s devastating ankle injury. Washington quarterbacks have thrown nine touchdowns in eight games. As for the Lions’ defense, that unit has given up 17 passing touchdowns while recording a mere five interceptions. The expectation here is that Smith will get back on track after a three-interception performance in Week 9.
Tampa Bay Buccaneers at Carolina Panthers
Buccaneers-Panthers Week 10 odds and point spread: Buccaneers -5.5 (over/under 50.0)
Related: Tom Brady statistical comparisons
Ouch. That’s the best way to describe Tom Brady’s performance in a 38-3 Week 9 blowout loss to the New Orleans Saints. He threw zero touchdowns compared to three interceptions. That came against a defense that had yielded 19 touchdowns and four interceptions heading into Sunday night’s outing. The moral of this story? I am not a fan of the Buccaneers at -5.5, given these recent events in this NFL Week 10 matchup.
NFL injury update: Latest injury news on fantasy stars for Week 10
Philadelphia Eagles at New York Giants
Eagles-Giants Week 10 odds and point spread: Eagles -4.0 (over/under 44.5)
The Eagles come off their Week 9 bye having won two consecutive games. Even more so than still-struggling quarterback Carson Wentz, Philadelphia’s defense has played a role in this. It is yielding an average of 15 points and has forced five turnovers in those to games. That came after the Eagles forced a total of five giveaways in their first six games. I like the Eagles here with Daniel Jones’ turnover proneness (21 interceptions, 25 fumbles in 21 career starts).
Jacksonville Jaguars at Green Bay Packers
Jaguars-Packers Week 10 odds point spread: Packers -13.5 (over/under 50.0)
Related: If you’re a fan of the Packers, check out #GoPackGo rumors, rankings, and news here
Green Bay was able to rebound last week after losing two of its previous three games. Aaron Rodgers got back on track and has now tallied 24 touchdowns compared to two interceptions on the season. As for the Jaguars, they have now lost seven in a row and are giving up an average of nearly 31 points per game. Quarterbacks are also on pace for 34 touchdowns and north of 4,500 passing yards against this team’s defense. You don’t need to do the math here.
Buffalo Bills at Arizona Cardinals
Bills-Cardinals Week 10 odds and point spread: Cardinals -2.5 (over/under 56.5)
Talk about taking a step back. Arizona’s defense has given up an average of 34 points over the past two games. Despite Kyler Murray’s ability to keep this team in games, that has to be concerning. This will also be magnified NFL Week 10 against Josh Allen and the Bills. He netted 415 passing yards and three touchdowns in a blowout Week 9 win over the Seahawks. If the point spread scares you off, go ahead and take the over. That will be met easily.
Los Angeles Chargers at Miami Dolphins
Chargers-Dolphins Week 10 odds and point spread: Dolphins -1.5 (over/under 48.5)
Related: NFL rookie rankings
Two of the top rookie quarterbacks going at it with Miami in the midst of a 5-3 start to the season. A lot of the recent focus has been on Tua Tagovailoa with the Dolphins. However, Justin Herbert continues to play great football in Southern California. The issue here for these Chargers is their inability to close out narrow games. As has been the case this season, it’s painted head coach Anthony Lynn in a bad light. Los Angeles has lost 15 of its past 18 one-score games. That will, again, be the case in Week 10.
Denver Broncos at Las Vegas Raiders
Broncos-Raiders Week 10 odds and point spread: Raiders -3.5 (over/under 50.5)
For only the second time since 2001, the Raiders boast a winning record after eight games. It took two consecutive wins, including the Chargers’ late-game struggles in Week 9. But this is a good position for Jon Gruden and Co. to be in right now. As for the Broncos, their three wins have all come against losing teams. In fact, Denver is 0-4 against winning squads and has been outscored by 52 points in those four games.
Related: 2022 NFL Power Rankings – Outlook for all 32 teams entering summer
Seattle Seahawks at Los Angeles Rams
Seahawks-Rams Week 10 odds and point spread: Rams -2.0 (over/under 54.0)
It’s simply astonishing how bad the Seahawks’ pass defense has been this season. Following last week’s brutal performance against the Bills, this unit is on pace to give up nearly 6,000 passing yards on the season. As for the Rams, they’ve yielded nine passing touchdowns compared to six interceptions and rank in the top-three of the NFL against the pass. Russell Wilson won’t be able to make that up here.
Cincinnati Bengals at Pittsburgh Steelers
Bengals-Steelers Week 10 odds and point spread: Steelers -7.5 (over/under 47.0)
Ben Roethlisberger’s questionable status should be talked about a whole heck of a lot here. He injured both knees in last week’s ugly win over the Dallas Cowboys. We know Big Ben is tough and will likely play. But consider for a second if he doesn’t. Since Pittsburgh selected Roethlisberger in the first round of the 2004 NFL Draft, the team is 23-17 in games he’s missed (.576 winning percentage). Big Ben boasts a career .679 winning percentage as a starter and with how this defense is playing, taking the under in a Steelers’ victory might be the right call.
San Francisco 49ers at New Orleans Saints
49ers-Saints Week 10 odds and point spread: Saints -10.0 (over/under 49.0)
Of the 24 starters on both sides of the during their Super Bowl loss this past February, six suited up last week. Currently, San Francisco has 21 players on reserve lists. As for the Saints, they are coming off a blowout 38-3 win over Tom Brady and the Buccaneers in Week 9. Even with such a big spread, expect New Orleans to cover at home. I am just not sure San Francisco can score enough for the over/under to be met.
Sunday Night Football Week 10
Baltimore Ravens at New England Patriots
Ravens-Steelers Week 10 odds and point spread: Ravens -7.0 (over/under 43.5)
Related: If you’re a fan of the Patriots, check out #GoPats rumors, rankings, and news here.
This has gotten ugly pretty darn quickly for Bill Belichick and the Patriots without Tom Brady in the mix. New England barely took out the Jets in Week 9, winning by the score of 30-27. That broke the Patriots first four-game losing streak 2000 and just the second time since 1993. You know what was happening back in 1993? Belichick was leading the Browns to a 7-9 record with Nick Saban as his defensive coordinator. Yeah, take the Ravens and the points.
Monday Night Football Week 10
Minnesota Vikings at Chicago Bears
Vikings-Bears Week 10 odds and point spread: Vikings -2.0 (over/under 43.0)
It now appears that it was right to call the Bears frauds following their 5-1 start to the season. Those five wins came against teams with a combined 17-27 record. Since then, Chicago has lost three consecutive and is averaging 16.7 points per game. On the other hand, Minnesota has ridden the dominance of Dalvin Cook to consecutive wins and an average of 31 points per outing. Look for these trends to continue in Week 10.
NFL Week 10 Thursday Night Football
Indianapolis Colts at Tennessee Titans
Colts-Titans Week 10 odds and point spread: Colts -1.5 (over/under 49.0)
Despite some struggles last week (10-of-21 passing), Ryan Tannehill is still in the midst of a franchise-record season for the Titans. Through the first eight games of the campaign, the former Miami Dolphins castoff is on pace for 40 total touchdowns compared to six interceptions. However, his Titans are just 2-1 against winning teams. He’s tallied an average of less than 200 passing yards in those three games. It’s certainly something to think about when checking the odds for this NFL Week 10 matchup.