Robert Deutsch-USA TODAY Sports

Cleveland Browns quarterback Baker Mayfield has thrown more interceptions than any player at his position since taking over as the team’s starter last season.

The San Francisco 49ers boast the NFL’s second-best defense and have been taking the ball away at an amazing clip this season.

Add those things together and it’s not a surprise that Mayfield has three first-half turnovers against the undefeated 49ers.

The third one was a killer. It came on third-and-goal from inside San Francisco’s 10 in the second quarter. Mayfield tried to find Antonio Callaway near the end zone.

The ball bounced off Callaway and into the hands of 49ers cornerback K’Waun Williams, who returned it 49 yards.

That’s what we’d call the bounces going in the wrong direction for Cleveland.

The good news? Cleveland’s first two turnovers resulted in zero points for San Francisco. The bad news? San Francisco turned this into seven and a 21-3 first-half lead.