Coach Mike Vrabel updated the status of his two top receivers on Friday.
Both players missed last Sunday’s 27-24 road loss to the New York Jets due to hamstring issues they sustained in a Week 3 win against the Indianapolis Colts. Brown returned to practice this week; Jones did not.
Jones, 32, has 12 catches for a team-leading 204 yards this season after joining the Titans in an offseason trade with the Atlanta Falcons in June.
A seven-time Pro Bowl selection through his first 10 seasons with Atlanta, Jones has 860 career receptions for 13,100 yards and 60 touchdowns.
Brown, 24, has just seven receptions for 92 yards and one touchdown in three games this season.
Last season, Brown caught 70 passes for 1,075 yards and 11 touchdowns in 14 games (12 starts) and made the Pro Bowl.
The Titans (2-2) have won the last three meetings against the AFC South rival Jaguars (0-4).
–Field Level Media