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San Francisco 49ers’ Justin Skule, Tarvarius Moore to miss 2021 season after injuries during OTA’s

Aug 19, 2019; Denver, CO, USA; San Francisco 49ers offensive tackle Justin Skule (67) before the game against the Denver Broncos at Broncos Stadium at Mile High. Mandatory Credit: Isaiah J. Downing-USA TODAY Sports

San Francisco 49ers offensive lineman Justin Skule and defensive back Tarvarius Moore likely will miss the upcoming season after sustaining significant injuries in an organized team activity.

Skule sustained a torn ACL in his knee and Moore a torn Achilles during Monday’s session. The San Jose Mercury News reported that the injuries prompted the 49ers to cancel Tuesday’s practice.

Skule, 24, has played in 31 regular-season games since being selected by San Francisco in the sixth round of the 2019 NFL Draft. He made 12 starts at tackle and guard.

Moore, 24, recorded 100 tackles, two forced fumbles and a fumble recovery in 48 career games (13 starts) since being selected by the 49ers in the third round of the 2018 NFL Draft.

Jaquiski Tartt likely will start at safety alongside Jimmie Ward in the secondary.

The 49ers addressed the secondary by signing safety Tony Jefferson to a one-year deal on Monday.

Jefferson, 29, has been out of football since tearing the ACL in his left knee in October 2019 while playing for the Baltimore Ravens. He has four career interceptions in 98 games (66 starts) with the Arizona Cardinals (2013-16) and Ravens (2017-19).

–Field Level Media