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49ers RB Elijah Mitchell (knee) ruled out vs. Titans

Sportsnaut
Sep 12, 2021; Detroit, Michigan, USA; San Francisco 49ers running back Elijah Mitchell (25) runs with the ball against the Detroit Lions during the fourth quarter at Ford Field. Mandatory Credit: Raj Mehta-USA TODAY Sports
Sep 12, 2021; Detroit, Michigan, USA; San Francisco 49ers running back Elijah Mitchell (25) runs with the ball against the Detroit Lions during the fourth quarter at Ford Field. Mandatory Credit: Raj Mehta-USA TODAY Sports

San Francisco 49ers running back Elijah Mitchell will miss Thursday night’s game against the host Tennessee Titans due to a knee injury.

It will be the second straight game that Mitchell sits out. He missed Sunday’s 31-13 victory over the Atlanta Falcons due to a concussion and a knee injury. He cleared concussion protocol earlier this week, and the 49ers were hoping the knee would respond.

Mitchell, a rookie, leads San Francisco with 759 rushing yards.

Jeff Wilson Jr. figures to receive most of the rushing work. Wilson rushed for a season-high 110 yards against Atlanta.

The 49ers also ruled out linebacker Dre Greenlaw (groin), safety Talanoa Hufanga (knee) and defensive lineman Maurice Hurst (calf). The club listed linebacker Azeez Al-Shaair (elbow) as questionable.

Safety Jaquiski Tartt (ankle) was a full practice participant on Wednesday and cleared to play.

–Field Level Media