The San Francisco 49ers 2016 Schedule for the regular season kicks off at home against the Los Angeles Rams and concludes in San Francisco against the Seattle Seahawks.

San Francisco 49ers 2016 Schedule

[mks_accordion]
[mks_accordion_item title=”Week 1 – Los Angeles Rams @ San Francisco 49ers”]
Date: Monday, September 12th, 2016
Television: 7:20pm PT on ESPN
Location: Levi’s Stadium
[/mks_accordion_item]
[mks_accordion_item title=”Week 2 – San Francisco 49ers @ Carolina Panthers”]
Date: Sunday, September 18th, 2016
Television: 10:00am PT on FOX
Location: Bank of America Stadium
[/mks_accordion_item]
[mks_accordion_item title=”Week 3 – San Francisco 49ers @ Seattle Seahawks”]
Date: Sunday, September 25th, 2016
Television: 1:05pm PT on FOX
Location: CenturyLink Field
[/mks_accordion_item]
[mks_accordion_item title=”Week 4 – Dallas Cowboys @ San Francisco 49ers”]
Date: Sunday, October 2nd, 2016
Television: 1:25pm PT on FOX
Location: Levi’s Stadium
[/mks_accordion_item]
[mks_accordion_item title=”Week 5 – Arizona Cardinals @ San Francisco 49ers”]
Date: Thursday, October 6th, 2016
Television: 5:25pm PT on CBS/NFL Network
Location: Levi’s Stadium
[/mks_accordion_item]
[mks_accordion_item title=”Week 6 – San Francisco 49ers @ Buffalo Bills”]
Date: Sunday, October 16th, 2016
Television: 10:00am PT on FOX
Location: Ralph Wilson Stadium
[/mks_accordion_item]
[mks_accordion_item title=”Week 7 – Tampa Bay Buccaneers @ San Francisco 49ers”]
Date: Sunday, October 23rd, 2016
Television: 1:05pm PT on FOX
Location: Levi’s Stadium
[/mks_accordion_item]
[mks_accordion_item title=”Week 8 – BYE”]
Date: Sunday, October 30th, 2016
[/mks_accordion_item]
[mks_accordion_item title=”Week 9 – New Orleans Saints @ San Francisco 49ers”]
Date: Sunday, November 6th, 2016
Television: 1:05pm PT on FOX
Location: Levi’s Stadium
[/mks_accordion_item]
[mks_accordion_item title=”Week 10 – San Francisco 49ers @ Arizona Cardinals”]
Date: Sunday, November 13th, 2016
Television: 1:25pm PT on FOX
Location: University of Phoenix Stadium
[/mks_accordion_item]
[mks_accordion_item title=”Week 11 – New England Patriots @ San Francisco 49ers”]
Date: Sunday, November 20th, 2016
Television: 1:25pm PT on CBS
Location: Levi’s Stadium
[/mks_accordion_item]
[mks_accordion_item title=”Week 12 – San Francisco 49ers @ Miami Dolphins”]
Date: Sunday, November 27th, 2016
Television: 10:00am PT on FOX
Location: Sun Life Stadium
[/mks_accordion_item]
[mks_accordion_item title=”Week 13 – San Francisco 49ers @ Chicago Bears”]
Date: Sunday, December 4th, 2016
Television: 10:00am PT on FOX
Location: Soldier Field
[/mks_accordion_item]
[mks_accordion_item title=”Week 14 – New York Jets @ San Francisco 49ers”]
Date: Sunday, December 11th, 2016
Television: 1:05pm PT on CBS
Location: Levi’s Stadium
[/mks_accordion_item]
[mks_accordion_item title=”Week 15 – San Francisco 49ers @ Atlanta Falcons”]
Date: Sunday, December 18th, 2016
Television: 1:05pm PT on FOX
Location: Georgia Dome
[/mks_accordion_item]
[mks_accordion_item title=”Week 16 – San Francisco 49ers @ Los Angeles Rams”]
Date: Saturday, December 24th, 2016
Television: 1:25pm PT on FOX
Location: LA Memorial Coliseum
[/mks_accordion_item]
[mks_accordion_item title=”Week 17 – Seattle Seahawks @ San Francisco 49ers”]
Date: Sunday, January 1st, 2017
Television: 1:25pm PT on FOX
Location: Levi’s Stadium
[/mks_accordion_item]
[/mks_accordion]

49ers Schedule Highlights

Thursday Night Football 2016 (CBS/NFL Network)
The 49ers play a Thursday Night Football game on October 6th in San Francisco against the Arizona Cardinals.

Sunday Night Football 2016
The 49ers do not play a Sunday Night Football game in 2016.

Monday Night Football 2016 (ESPN)
The 49ers play a Monday Night Football game on September 12th in San Francisco against the Los Angeles Rams.

In total, the San Francisco 49ers 2016 Schedule includes two nationally televised games. Read more about the San Francisco 49ers 2016 Season here.